Chronic Radiation Exposure: Low-Dose Effects


Program of the
IV International Conference

Chronic Radiation Exposure: Low-Dose Effects
Chelyabinsk, Russia, November 9 – 11, 2010

Tuesday, November 9

8.00 – 9.00Registration of conference participants


9.00 – 9.30 Formal greetings:
  • M.F. Kiselyov (Federal Medical-Biological Agency)
  • A.J. González (International Commission on Radiological Protection)
  • Zh. Carr (World Health Organization)
  • V.V. Sadyrin (Chelyabinsk Oblast Ministry of Education and Science)


9.30 – 9.50
V.F. Kiselyov
Role played by the FMBA of Russia in assurance of radiation safety in the Southern Urals
9.50 – 10.00
B. Fountos
Recent research results from the Russian health studies program
10.00 – 10.20
J. Harrison
EU supported epidemiological studies in the Southern Urals: SOUL progress and SOLO proposals
10.20 – 10.40COFFEE BREAK
10.40 – 11.00
S. Salomaa, W. Weiss, J. Repussard, G. Bloch, F. Hardeman, V. Macellari, J. Harrison, M. Harms-Ringdahl, P. Vaz, F. Zölzer, A. Jouve, D. Averbeck, A. Ottolenghi, L. Sabatier, M. Atkinson, S. Bouffler, P. Gourmelon, J.-R. Jourdain, G. Simone, S. Baatout, T. Jung, E. Cardis and J. Hall. Presenter: E. Salminen
European low dose risk research strategy
11.00 – 11.20
Zhanat Carr
WHO program on radiation health
11.20 – 11.50
A.J. González
Lecture: Attributing risks and effects to low-dose radiation exposure situations

Chairs: I.I. Pelevina, M.F. Kiselyov, O. Niwa

11.50 – 12.20
T.M. Fliedner and D.H. Graessle
Pathogenesis of hematopoietic failure after exposure to chronic or protracted ionising radiation: a disturbance of cellular kinetics
12.20 – 14.00LUNCH
14.00 – 14.25
I.I. Pelevina
Relationship between cytogenetic characteristics of human blood lymphocytes and oxidative stress parameters under exposure to radiation and other factors
14.25 – 14.50
S. Tapio, F. Pluder, R. Yentrapalli, Z. Barjaktarovic, O. Azimzadeh, M. Harms-Ringdahl, A. Wojcik, S. Haghdoost, M.J. Atkinson
Dose rate effects on the radiation response of primary endothelial cells and endothelial cell lines analyzed by different proteomic approaches
14.50 – 15.15
M.W. Epperly, J.A. Jones, C. Montesinos, T.M. Dixon, H. Wang, J.S. Greenberger
Consumption of a high antioxidant diet decreases life shortening in mice after total body irradiation, implications for chronic radiation exposure

Chairs: A. González, Yu.M. Zakharov, J. Jones

15.15 – 15.55
R.E. Shore
Lecture: The Japanese A-bomb survivor data and studies of low-dose effects
15.55 – 16.20
R.M. Takhauov
The main approaches to evaluation of long-term radiation exposure in a range of "low" doses
16.20 – 16.40COFFEE BREAK
16.40 – 17.05
P. Schneider, J. Biko
Case report of a renal cell carcinoma and radiation associated probability of causation
17.05 – 17.30
A.V. Akleyev, T.A. Varfolomeyeva, G.P. Dimov, I.A. Akushevich, G.A. Veremeyeva
Reaction of hemopoiesis to chronic low-dose rate exposure in residents of Techa riverside villages.
17.30 – 17.55
A.V. Akleyev, A.V. Aleshenko, .V. Kudryashova, L.P. Semenova, .. Serebryanyi, .I. Khudyakova, I.I. Pelevina
Adaptive response of blood lymphocytes as indicator of hematopoietic status in radiation-exposed people
17.55 – 18.20
O.F. Kalyov, N.G. Kalyova, D.K. Volosnikov, N.A. Ralnikova, G.Ya. Galimova
Chronic disorders in adolescents resident in the Techa River floodplain area
18.20 – 18.45
E.N. Kirillova, M.L. Zakharova, K.N. Muksinova, E.D. Drugova, O.S. Pavlova, S.N. Sokolova
Quantitative assessment and informativity of regulatory proteins in blood as radiation markers in the long-term period after occupational exposure at different doses
19.30 – 21.00
Conference Opening Reception

Wednesday, November 10

Chairs: D. Preston, N. A. Koshurnikova, B. Fountos

8.30 – 8.55
N.A. Koshurnikova, L.Ya. Kaygorodova, I.S. Kuznetsova, E.I. Rabinovich, E.I. Masharova, I.A. Martinenko, V.S. Alekseev, N.T. Panteleev, L.A. Sannikova,T.V. Ryzhikh
Thyroid cancer at technogenic exposure in childhood
8.55 – 9.20
D.L. Preston, L.Yu. Krestinina, E. Ron, F.G. Davis, S. Epifanova, S. Schonfeld, M.O. Degteva, A.V. Akleyev
The impact of the new dosimetry system on solid cancer risk estimates for the Techa river cohort
9.20 – 9.45
L.Yu. Krestinina, S.B. Epifanova, A.V. Akleyev, S.S. Silkin, L.D. Mikryukova, M.O. Degteva, N.B. Shagina
Estimation of radiogenic risk of mortality from cardio-vascular disorders under chronic low-dose exposure of Techa River cohort (TRC) members
9.45 – 10.10
T.V. Azizova, C.R. Muirhead, M.B. Moseeva, E.S. Grigoryeva, E.V. Vlasenko, M.V. Sumina, J.A. OHagan, W. Zhang, R.G.E. Haylock, N. Hunter
Radiation risks of incidence and mortality from ischemic heart disease and cerebrovascular diseases among the Mayak PA nuclear workers
10.10 – 10.35
J.P. Garsi, I. Guseva Canu, E. Cardis, S. Caër-Lorho, A. Acker, M. Tirmarche, D. Laurier
Relationship between occupational exposure to uranium and cardiovascular mortality
10.35 – 10.55COFFEE BREAK
10.55 – 11.20
.B. rpov, Yu.V. Semenova, .. Litvinenko, R.. khauov
The evaluation of nononcological effects of the long-term radiation exposure in a range of low doses
11.20 – 11.45
A.K. Guskova, I.A. Gusev
Principal sources of errors in interpretation of data on small-dose effects in humans
11.45 – 12.10
A.V. Rubanovich
Introduction to meta-analysis
12.10 – 14.00LUNCH
14.00 – 14.30POSTER SESSION
14.30 – 14.55
S.J. Schonfeld, P. Bhatti, E.E. Brown, M.S. Linet, S.L. Simon, R.M. Weinstock, A.A. Hutchinson, M. Stovall, D.L. Preston, B.H. Alexander, M.M. Doody, A.J. Sigurdson
Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among U.S. radiologic technologists
14.55 – 15.20
N.V. Litvyakov, O.O. Goncharik, R.M. Takhauov, A.B. Karpov, A.M. Ageeva, S.A. Mezheritsky, E.O. Vasilyeva
Allelic imbalance of genes in sporadic tumor tissue and in tumors which were apeared on the background of the low intensity irradiation
15.20 – 15.45
M.Y. Guryanov, G.G. Rusinova, M.V. Kartashova
Role of the GSTM1, GSTT1, CYP1A1, CYP2E1, EPHX1, NAT2, and TP53 genes in late effects of radiation exposure in plutonium workers at the MAYAK PA

Chairs: K. Streffer, A.V. Akleyev, R. Shore

15.45 – 16.10
E.I. Rabinovich, S.V. Povolotskaya, V.A. Turdakova, E.F. Ryzhova
The realization of hereditary predisposition to thyroid diseases in the offspring of parents exposed to radioactive iodone in childhood
16.10 – 16.30BREAK
16.30 – 16.55
V.I. Telnov, N.R. Kabirova, P.V. Okatenko
Preconceptual exposure of fathers and cancer risk in offsprings
16.55 – 17.20
I.V. Glazkova, G.G. Rusinova, M.V. Kartashova, N.S. Vyazovskaya
Study on genomic instability in families of the MAYAK workers using minisatellite markers

Chairs: G.M. Rumyantseva, D. Rush, E.Yu. Burtovaya

17.20 – 17.45
G.M. Rumyantseva, O.V. Chinkina
Comprehensive estimation of damage to mental health in persons exposed to uncontrolled high-level ionizing radiation
17.45 – 18.10
E.Yu. Burtovaya, A.V. Akleyev, V.M. Ivanov, O.G. Samsonova, M.V. Belova, T.A. Varfolomeyeva
Psychosomatic status in residents of Muslyumovo village, Chelyabinsk oblast, at the time of resettlement
18.10 – 18.35
V.A. Rudnitsky, L.N. Avdeenok, V.Ya. Semke
Clinical and rehabilitation aspects of non-psychotic mental disorders among ChAPS accident cleanup workers

Thursday, November 11

Chairs: L. Anspaugh, M. Degteva, J. Harrison

8.30 – 8.55
J. Harrison, W. Bolch, H. Menzel
The work of ICRP Committee 2 on dosimetry and its relevance to epidemiological studies
8.55 – 9.20
T. Imanaka
Reconstruction of residual radiation exposure by the atomic bombing in Hiroshima
9.20 – 9.45
B.A. Napier, M.O. Degteva, N.B. Shagina, L.R. Anspaugh
Uncertainty analysis for the Techa river dosimetry system
9.45 – 10.10
M. Degteva, N. Shagina, M. Vorobiova, E. Shishkina, L. Anspaugh, and B. Napier
Re-evaluation of the Techa River source term: impact on dose estimates for exposed populations of the riverside communities
10.10 – 10.35
A. Birchall, M. Puncher, D. Strom, R. Scherpelz, A. Shadilov and S. Romanov
An overview of recent developments in plutonium lung dosimetry
10.35 – 10.55BREAK
10.55 – 11.20
A. Wieser, E. Vasilenko, S. Romanov, T. Azizova, E. Ainsbury, F. Darroudi, P. Fattibene, P. Jacob
Strategy for improvement of external dose estimates from the MAYAK dosimetry system
11.20 – 11.45
Yu.G. Mokrov
Retrospective Estimation of Dose Impact to Population Due to I-131 Atmospheric Releases from Mayak PA Sources (1949-1965)
11.45 – 12.0
D.J. Strom, K.E. Joyce, J.A. MacLellan, D.J. Watson, T.P. Lynch, C.A. Antoni, A.Birchall, P.A. Zharov
Separating measurement error from population variability to produce a distribution of possibly true results
12.10 – 14.00LUNCH

Chairs: A.K. Guskova, G. Reeves, T.V. Azizova

14.00 – 14.25
T.V. Azizova, D.J. Brenner, N.V. Sotnik
Calibrated biodosimetry system for separate assessment of internal and external exposure in Russian nuclear workers
14.25 – 14.50
V.A. Timoshevsky, I.N. Lebedev, S.A. Vasilyev, N.N. Sukhanova, Yu.S. Yakovleva, N.B. Torkhova
Effects of low doses of Plutonium-239: chromosome and cytomic abnormalities in somatic cell in workers of a radiochemical facility
14.50 – 15.15
G.P. Snigiryova, A.L. Neverova, E.A. Aseeva, N.N. Novitskaya, E.D. Khazins, E.V. Domracheva
The multiaberrant cells as a biomarker of high let energy exposure to human organism
15.15 – 15.40
A. Vozilova, N. Shagina, M. Degteva, A. Edwards, E. Ainsbury, J. Moquet, P. Hone, D. Lloyd, J. Fomina and F. Darroudi
Preliminary FISH-based assessment of external doses for the Techa river residents
15.40 – 16.05
S.V. Osovets, T.V. Azizova, N.V. Sotnik
Uncertainties of dose estimates from the group biodosimetry based on cytogenetic data
16.05 – 16.20COFFEE BREAK

Chairs: V.G. Zainullin, B. Napier

16.20 – 16.45
V.G. Zainullin, E.A. Yushkova
Radiation-induced genetic effects in Drosophila Melanogaster.
16.45 – 17.10
E.A. Pryakhin, G.A. Tryapitsina, L.V. Deryabina, P.M. Stukalov, B.A. Kostyuchenko, A.V. Akleyev
Comprehensive assessment of ecosystems status in industrial reservoirs of the MAYAK PA
17.10 – 17.35
A.V. Trapeznikov, V.N. Trapeznikova, A.V. Korzhavin, V.I. Migunov, Ya.G. Chubarov
Results of a radioecological study of small rivers in the Irtysh River basin on the territory of the Khanty-Mansi (Ugra) autonomous district
17.35 – 18.00
S.G. Levina, A.V. Akleyev, V.V. Deryagin, A.A. Sutyagin, I.Ya. Popova
Migration of long-lived radionuclides in lacustrine ecosystems in the north of Chelyabinsk oblast
18.00 – 18.25
V.A. Kostyuchenko, L.M. Peremyslova, I.Ya. Popova, N.N. Kazachonok, V.S. Melnikov, D.V. Usoltsev
The comparative characteristic of the long-lived radionuclides migration in soil-human chain in long-term post radiation accident period
18.25 – 18.55
Summing-up and closure of the Conference

Thursday, November 11

15.40 – 17.40Round table discussion devoted to radiation risk analysis based on data from unified databases
Moderators: J. Shuz, M.E. Sokolnikov
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